ForCast Orthopedics, KORU Medical Systems Partner on Antibiotic Infusion Therapy

ForCast Orthopedics Inc. and KORU Medical Systems Inc. have negotiated an agreement to leverage KORU Medical’s FreedomEDGE infusion system as part of ForCast’s technology platform for periprosthetic joint infection (PJI) treatment. PJI is a rare but serious complication of joint replacement procedures, and is challenging to treat because the infecting bacteria adhere to the prothesis and can form a protective biofilm that is resistant to standard systemic antibiotics.

KORU Medical’s FreedomEDGE pump will provide the infusion technology to support ForCast’s proprietary delivery system for PJI treatment, known as WIIS (Wearable Intra-Articular Infusion System), in anticipation of starting a clinical trial next year.

“We are excited to kick off this development program with KORU,” ForCast Executive Chairman/CEO Peter Noymer, Ph.D., said. “After reviewing the entire landscape of infusion pump technologies available, it became clear that KORU’s products were best suited for partnering with our WIIS platform and for meeting the needs of PJI patients.”

ForCast’s lead program, FC001, has received both Orphan Drug Designation and Qualified Infectious Disease Program (QIDP) designation from the U.S. Food and Drug Administration (FDA), which enable eligibility for Fast-Track Designation and Priority Review.

“We look forward to working with ForCast and helping them achieve their mission to modernize the standard of care for PJI,” KORU Medical President/CEO Linda Tharby stated. “Supporting such a novel delivery system highlights the utility of the Freedom System and we are proud to be a trusted supplier for our partners.”

ForCast Orthopedics is a development-stage company development a treatment for PJI using targeted antibiotic therapy. ForCast’s mission is to modernize PJI care and improve the quality of life for joint replacement patients.

KORU Medical develops, manufactures, and commercializes patient-centric large volume subcutaneous infusion solutions that improve patients’ quality of life. The Freedom Syringe Infusion System currently includes the Freedom60 and FreedomEDGE Syringe Infusion Drivers, Precision Flow Rate Tubing, and HigH-Flo Subcutaneous Safety Needle Sets. The Freedom System, which received its first FDA clearance in 1994, is used for self-administration in the home by the patient and/or delivery in an ambulatory infusion center by a healthcare professional. Through its Pharma Services and Clinical Trials business, KORU Medical provides products for use by biopharmaceutical companies in feasibility/clinical trials during the drug development process and, as needed, is capable of customizing the Freedom System for clinical and commercial use across multiple drug categories.